Proton Pump Inhibitors (PPIs)
Introduced in the late 1980s, PPIs are used for the treatment of acid-related disorders of the upper gastrointestinal tract, including peptic ulcers and gastrointestinal reflux disorders. Long-term use of PPIs, including Prilosec, Prevacid and Nexium, may result in Acute Interstitial Nephritis (AIN), which is a condition where the spaces between the tubules of the kidney cells become inflamed. While individuals who suffer from AIN can recover, most will suffer from some level of permanent kidney function loss. In rare cases, individuals suffering from PPI-induced AIN will require kidney transplant. The Dugan law Firm is accepting clients who took PPIs and suffered injuries.
The most serious potential side effects and risks caused through the use of PPIs are strokes, bone fractures, kidney disease, renal failure and heart damage.
People who take multiple daily doses for a long period of time (over a year), especially those over 50 , have an increased risk of fractures of the hip, wrist, and spine. Additionally, people who use the drugs appear to have a 20-50% higher risk of chronic kidney disease compared with nonusers, and a 20-30% increased risk for stroke.