The drug Invokana, approved by the FDA in March 2012, is classified as an SGLT2 inhibitor, which works by reducing blood sugar levels in Type 2 diabetes patients. Invokana has been linked to Gangrene of the genitals, Genital Amputations, and a number of serious kidney problems, including kidney damage and ketoacidosis, a serious buildup of acids in the blood that can be life threatening if left untreated. Current Invokana lawsuits being filed claim the manufacturers failed to warn patients and physicians of the increased risks of kidney failure, ketoacidosis, and leg and foot amputations.
The FDA released this warning August 29, 2018:
The U.S. Food and Drug Administration (FDA) is warning that cases of a rare but serious infection of the genitals and area around the genitals have been reported with the class of type 2 diabetes medicines called sodium-glucose cotransporter-2 (SGLT2) inhibitors. This serious rare infection, called necrotizing fasciitis of the perineum, is also referred to as Fournier’s gangrene. We are requiring a new warning about this risk to be added to the prescribing information of all SGLT2 inhibitors and to the patient Medication Guide.
Those medications include Invokana, Invokamet, Farxiga, and Jardiance. The Dugan law Firm is accepting clients who took Invokana and suffered injuries.
Diabetes Type 2 Medications
- Invokana (canagliflozin)
- Invokamet (canagliflozin/metformin)
- Jardiance (empagliflozin)
- Xigduo XR (dapagliflozin/metformin)
- Farxiga (dapagliflozin)
- Glyxambi (empagliflozin/linagliptin)
FDA Warning for Type 2 Diabetes Meds Invokana, Invokamet
FDA reviewed 20 adverse event reports from people seriously injured or hospitalized after taking type 2 diabetes drugs that included Invokana and Invokamet. These drugs belong to a class of medications known as sodium-glucose cotransporter-2 (SGLT2) inhibitors. They were approved by FDA to lower blood sugar levels in adults suffering from type 2 diabetes. The FDA announcement warned patients to seek immediate medical help for symptoms of ketoacidosis.
Symptoms include several potentially serious health issues:
- Difficulty breathing
- Abdominal pain
- Confusion Unusual fatigue or sleepiness
What is Invokana?
- A prescription drug made by Janssen Pharmaceuticals, a division of Johnson & Johnson.
- A drug meant to lower blood sugar in type 2 diabetic adults
- Not for people with type 1 diabetes
- Not for those with diabetic ketoacidosis (increased ketones)
- Not proven safe and effective for children under 18.
Invokana hit the market in May 2013, with a heavy and successful marketing campaign. Johnson & Johnson reported 2014 sales of Invokana totaling $569 million. Sales for 2015 total $266 million as of June 2015. Those are heavy sales for any drug, much less one as new as Invokana. Thousands of claims have been filed against Johnson & Johnson and Janssen Pharmaceuticals by individuals who have suffered injuries as a result of taking Invokana. The lawsuits are presently combined before a federal judge in New Jersey, where all of the national discovery and evidence gathering is taking place. Invokana has been linked to kidney damage, ketoacidosis and amputations.
The most serious potential side effects and risks caused by Invokana include:
- Gangrene of the genitals
- Kidney Damage
- Heart Attack